| 产品详情 |
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| Antigenic Specificity | CD171 |
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| Clone | L1.1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD171 Monoclonal Antibody (L1.1). L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. |
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| Immunogen | n/a |
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| Other Names | CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, S10, SPG1 |
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| Gene, Accession # | Entrez: 3897; Uniprot: P32004 |
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| Catalog # | 37-5100 |
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| Price | |
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| Order / More Info | CD171 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10861797, 9245498 |
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