| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | JMJD1A |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, nonhuman primate |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:500-1:2000, Immunofluorescence: 1:500-1:2000, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:5000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | JMJD1A Polyclonal Antibody. JMJD1A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. JMJD1A is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. It's also Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging an |
|---|
| Immunogen | n/a |
|---|
| Other Names | JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA, jmjC domain-containing histone demethylation protein 2A, jumonji C domain-containing histone demethylase 2A, jumonji domain containing 1, jumonji domain containing 1A, jumonji domain-containing protein 1A, lysine-specific demethylase 3A, testis-specific protein A |
|---|
| Gene, Accession # | Entrez: 104263, 55818; Uniprot: Q6PCM1, Q9Y4C1 |
|---|
| Catalog # | PA5-23066 |
|---|
| Price | |
|---|
| Order / More Info | JMJD1A Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|