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| Antigenic Specificity | APP (pT743) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APP (pT743) Antibody is a Rabbit Polyclonal antibody against APP (pT743). This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
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| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T743 of human APP. |
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| Other Names | AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; PreA4; Protease nexin-II; Amyloid Beta (A4) Precursor Protein; Beta-Amyloid Peptide; A4; Amyloid beta A4 protein; N-APP; Soluble APP-alpha; Soluble APP-beta; C99; Beta-amyloid protein 42; Beta-APP42; Beta-amyloid protein 40; Beta-APP40; C83; P3 (42); P3 (40); C80; Gamma-secretase C-terminal fragment 59; Amyloid intracellular domain 59; Gamma-CTF (59); Gamma-secretase C-terminal fragment 57; Amyloid intracellular domain 57; Gamma-CTF (57); Gamma-secretase C-terminal fragment 50; Amyloid intracellular domain 50; Gamma-CTF (50); C31; CTFgamma; amyloidP; Beta Amyloid |
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| Gene, Accession # | APP, Gene ID: 4609, SwissProt: P05067 |
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| Catalog # | abx000096 |
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| Price | |
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| Order / More Info | APP (pT743) Antibody from ABBEXA |
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| Product Specific References | n/a |
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