| 产品详情 |
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| Antigenic Specificity | CD63 |
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| Clone | NVG-2 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-mouse CD63. CD63, also known as LIMP, LAMP-3, gp55, and melanoma-associated antigen (ME491), is a member of the tetraspanin superfamily (TM4SF) that constitutes a main component of the lysosomal membrane. It is expressed on activated platelets, monocyte/macrophages, endothelium, fibroblasts, osteoblasts, and smooth muscle cells. CD63 may be involved in platelet activation and is thought to function as a transmembrane adaptor protein. CD63 has been shown to associate with CD9, CD81, VLA-3, and VLA-6. In mice, there are two CD63 gene loci, of which only one is functional. CD63 deficient mice are viable, and there is no alteration in the population of immune cells. A recent report shows that CD63-deficient mice exhibit a significant reduction in both leukocyte rolling and recruitment in a peritonitis model. |
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| Immunogen | Intestinal lamina propria light-density cells (enriched with eosinophils) |
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| Other Names | LIMP, LAMP-3, gp55, melanoma-associated antiben, ME491 |
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| Gene, Accession # | Gene ID: 12512 |
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| Catalog # | 143906 |
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| Price | |
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| Order / More Info | CD63 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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