| 产品详情 |
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| Antigenic Specificity | CD61 |
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| Clone | 2C9.G2 (HMβ3-1) |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse/rat CD61. CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv/β3 integrin or vitronectin receptor to CD31 (PECAM-1). |
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| Immunogen | Vitronectin receptor protein from the mouse T-cell hybridoma 2B4 |
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| Other Names | β3 integrin, Integrin β3 chain, gpIIIa |
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| Gene, Accession # | Gene ID: 16416, 29302 |
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| Catalog # | 104302 |
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| Price | |
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| Order / More Info | CD61 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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