产品详情 |
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Antigenic Specificity | CD61 |
Clone | VI-PL2 |
Host Species | Mouse |
Reactive Species | human, African green, baboon, cynomolgus, rhesus |
Isotype | IgG1, κ |
Format | PerCP-Cyanine5.5 conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PerCP/Cyanine5.5 anti-human CD61. CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins. |
Immunogen | n/a |
Other Names | Integrin β3, gpIIIa |
Gene, Accession # | Gene ID: 3690 |
Catalog # | 336417 |
Price | |
Order / More Info | CD61 Antibody from BIOLEGEND |
Product Specific References | n/a |
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