产品详情 |
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Antigenic Specificity | VANGL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | canine, human, mouse, nonhuman primate, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 4-6 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VANGL2 Polyclonal Antibody. Van Gogh is an alternate name for the Drosophila strabismus protein. Van Gogh like-2 (VANGL2) is a 521 amino acid protein in vertebrates similar to strabismus 1 of Drosophila and a component of the frizzled-dishevelled tissue polarity pathway. It interacts through it's C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3 and is a potent tumour suppressor. It is predominantly involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a crucial role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. VANGL2 is required for polarization and movement of myocard |
Immunogen | n/a |
Other Names | LPP1, LTAP, STB1, STBM, STBM1, loop-tail protein 1 homolog, loop-tail-associated protein, strabismus 1, van Gogh-like protein 2, vang-like protein 2 |
Gene, Accession # | Entrez: 289229, 57216, 610037, 93840; Uniprot: P84889, Q91ZD4, Q9ULK5 |
Catalog # | PA5-23207 |
Price | |
Order / More Info | VANGL2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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