产品详情 |
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Antigenic Specificity | VANGL1 |
Clone | CL0241 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VANGL1 Monoclonal Antibody (CL0241). Vang-like 1 protein is a novel human homologue of Drosophila Van Gogh/Strabismus. The Vang-like 1 gene consists of at least 7 exons, and encodes a protein with four transmembrane domains and the C-terminal Ser/Thr-X-Val motif. Studies shows that the expression of the protein is significantly up-regulated in gastric cancer cell lines MKN28, MKN74, pancreatic cancer cell lines BxPC-3, PSN-1 and Hs766T. The protein may serve as an effector mediating the intestinal trefoil factor (ITF) healing response of the intestinal mucosa. The protein also serves as a diagnostic marker for hepatocellular carcinoma as well as a potential molecular target for development of novel therapeutic drugs. The pathological role o |
Immunogen | n/a |
Other Names | KITENIN, LPP2, STB2, STBM2, KAI1 C-terminal interacting tetraspanin, loop-tail protein 2 homolog, strabismus 2, van Gogh-like protein 1, vang-like protein 1 |
Gene, Accession # | Entrez: 81839; Uniprot: Q8TAA9 |
Catalog # | MA5-24592 |
Price | |
Order / More Info | VANGL1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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