| 产品详情 |
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| Product Name | AM251 |
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| Description | A CB1 antagonist and CB2 inverse agonist; Kis = 7.5 and 2,290 nM for CB1 and CB2 from rat forebrain and mouse spleen, respectively; agonist at GPR55 (EC50 = 39 nM); potentiates GABAA currents (EC50 = 0.4 µM); prevents TGF-β1-induced EMT in HK-2 renal tubule epithelial cells independent of CB receptors or GPR55; halts the cell cycle and induces apoptosis in A375 human melanoma cells; reduces antidepressant-like behavior and decreases fasting-induced hyperphagia in mice |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CB-1 2 AM-251 GPR-55 GABA-A TGFβ1 HK2 SMAD-2 3 |
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| Gene, Accession, CAS # | CAS: 183232-66-8 |
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| Catalog # | 71670-5 |
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| Order / More Info | AM251 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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