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| Antigenic Specificity | GPLD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:20-1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GPLD1 Polyclonal Antibody. GPLD1 is expressed in numerous tissues and cells and specifically cleaves GPI-anchored proteins. Liver has the highest level of GPI-PLD expression and is the primary organ contributing to GPLD1 in the serum. GPLD1 is abundant in serum in which it associates with polipoproteins AI and AIV. Increased serum GPLD1 is associated with insulin resistance and elevated serum triglycerides. Many surface proteins are attached to eukaryotic cell membranes via glycosylphosphatidylinositol (GPI) anchors that are covalently bound to the C-terminus of the protein and cleavage of the GPI moiety by GPLD1, only enzyme known that cleavage GPI anchor, may represent a means of regulating attachment of these proteins to the cell surface |
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| Immunogen | n/a |
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| Other Names | Phosphatidylinositol-glycan-specific phospholipase D; PI-G PLD; Glycoprotein phospholipase D; Glycosyl-phosphatidylinositol-specific phospholipase D; PIGPLD1 |
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| Gene, Accession # | Entrez: 2822; Uniprot: P80108 |
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| Catalog # | PA5-52941 |
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| Price | |
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| Order / More Info | GPLD1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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