| 产品详情 |
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| Product Name | Indisulam |
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| Description | A sulfonamide with anticancer activity (IC50s = 0.11 and 94 µg/ml, for HCT116 and NCI-H596 cells, respectively); increases the number of P388 murine leukemia cells in the G1 phase of the cell cycle in a dose-dependent manner; exerts time-dependent cytotoxicity against HCT116 cells; suppresses tumor growth and decreases tumor volume in murine HCT116, SW620, and HCT15 colorectal and LX-1 and PC9 lung cancer xenograft models; induces proteasomal degradation of RBM39 through association with the CUL4-DCAF15 E3 ubiquitin ligase in vitro; an inhibitor of carbonic anhydrase in H. pylori (Ki = 310-562 nM), |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | E-7070 |
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| Gene, Accession, CAS # | CAS: 165668-41-7 |
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| Catalog # | 22759-10 |
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| Price | |
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| Order / More Info | Indisulam from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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