| 产品详情 |
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| Product Name | AS-604850 |
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| Description | AS-604850 is a selective, ATP-competitive inhibitor of PI3Kγ with IC50 values of 0.25, >20, >20, and 4.5 µM for the human recombinant γ, .delta., β, and α isoforms, respectively.{13338} AS-604850 inhibited MCP-1-mediated monocyte chemotaxis with an IC50 value of 21 µM and reduced RANTES-induced peritoneal neutrophil recruitment in a murine model of leukocyte chemotaxis with an ED50 value of 42.4 mg/kg.{13338} |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | phosphoinositides 3-kinases PI3-kinase PI3-K phosphatidylinositol inflammatory drugs inflammation arthritis rheumatoid peritonitis neutrophils recruitment PtdIns inhibitors inhibits inhibiton PI3K AS604850 AS 604850 |
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| Gene, Accession, CAS # | CAS: 648449-76-7 |
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| Catalog # | 10010175-5 |
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| Order / More Info | AS-604850 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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