| 产品详情 |
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| Antigenic Specificity | HIST1H2BA |
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| Clone | OTI1C9 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HIST1H2BA Monoclonal Antibody (OTI1C9). Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones. Also expressed maternally and is present in the female pronucleus, suggesting a similar role in protamine replacement by nucleosomes at fertilization. Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear. Core component of nucleosome. Nucleosomes wrap and compact DNA into chrom |
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| Immunogen | n/a |
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| Other Names | Histone H2B type 1-A, Histone H2B, testis, TSH2B1, Testis-specific histone H2B, HIST1H2BA, TSH2B |
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| Gene, Accession # | Entrez: 255626; Uniprot: Q96A08 |
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| Catalog # | MA5-26966 |
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| Price | |
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| Order / More Info | HIST1H2BA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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