产品详情 |
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Product Name | OTS514 |
Description | An inhibitor of TOPK (IC50 = 2.6 nM); selectively inhibits growth of patient-derived AML cells over normal CD34+ cells; inhibits growth of small cell lung, kidney, and ovarian cancer cell lines (IC50s = 0.4-42.6 nM); increases survival in a peritoneal mouse dissemination model of ovarian cancer at 25 and 50 mg/kg; dose-dependently inhibits tumor growth in an A549 mouse xenograft model at 1, 2.5, and 5 mg/kg |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | 1338541-25-5 1338544-87-8 1338545-92-8 OTS-514 CD-34 A-549 |
Gene, Accession, CAS # | CAS: 1338540-63-8 |
Catalog # | 17053-500 |
Price | |
Order / More Info | OTS514 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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