| Edit |   |
| Antigenic Specificity | APC (pS2054) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Phospho-APC (Ser2054) Antibody detects endogenous levels of APC only when phosphorylated at Sersine 2054. This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Immunogen | n/a |
| Other Names | Adenomatosis Polyposis Coli Protein; APC; DP2; DP2.5; DP3; FAP; FPC; GS; Deleted in polyposis 2.5; APC protein; Adenomatous polyposis coli protein; mAPC; Protein APC |
| Gene, Accession # | APC, Gene ID: 324, SwissProt: P25054 |
| Catalog # | abx012104 |
| Price | |
| Order / More Info | APC (pS2054) Antibody from ABBEXA |
| Product Specific References | n/a |