产品详情 |
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Antigenic Specificity | TrxR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TrxR2 Polyclonal Antibody. The mammalian thioredoxin reductases (TrxRs) are a family of selenocysteine-containing pyridine nucleotide-disulfide oxidoreductases. All the mammalian TrxRs are homologous to glutathione reductase with respect to primary structure including the conserved redox catalytic site (-Cys-Val-Asn-Val-Gly-Cys-) but distinctively with a C-terminal extension containing a catalytically active penultimate selenocysteine (SeCys) residue in the conserved sequence (-Gly-Cys-SeCys-Gly). TrxR is homodimeric protein in which each monomer includes an FAD prosthetic group, a NADPH binding site and a redox catalytic site. Electrons are transferred from NADPH via FAD and the active-site disulfide to C-terminal SeCys-containing redox ce |
Immunogen | n/a |
Other Names | trxR2 |
Gene, Accession # | Entrez: 10587, 26462, 50551; Uniprot: Q9JLT4, Q9NNW7, Q9Z0J5 |
Catalog # | LF-PA0024 |
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Order / More Info | TrxR2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 25955690 |
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