产品详情 |
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Antigenic Specificity | TrxR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TrxR2 Polyclonal Antibody. The reduced form of thioredoxin serves as a hydrogen donor, contributes to the up-regulation of various transcription factors and binds to and inhibits MAPKKK activity. Oxidized thioredoxin is converted back to the reduced form by Thioredoxin Reductase (TrxR2), a redox active enzyme. There are two distinct isoforms in mammalian cells, TrxR1, a cytosolic protein and TrxR2, almost exclusively a mitochondrial protein. TrxR expression is induced in several tumors. |
Immunogen | n/a |
Other Names | SELZ, TR, TR-BETA, TR3, TRXR2, selenoprotein Z, thioredoxin reductase 2, mitochondrial, thioredoxin reductase 3, thioredoxin reductase TR3, thioredoxin reductase beta |
Gene, Accession # | Entrez: 10587; Uniprot: Q9NNW7 |
Catalog # | PA1-38805 |
Price | |
Order / More Info | TrxR2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
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