| 产品详情 |
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| Antigenic Specificity | TrxR1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TrxR1 Polyclonal Antibody. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing |
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| Immunogen | n/a |
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| Other Names | GRIM-12, TR, TR1, TRXR1, TXNR, KM-102-derived reductase-like factor, gene associated with retinoic and IFN-induced mortality 12 protein, gene associated with retinoic and interferon-induced mortality 12 protein, oxidoreductase, thioredoxin reductase 1, cytoplasmic, thioredoxin reductase GRI |
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| Gene, Accession # | Entrez: 50493, 58819, 7296; Uniprot: O89049, Q16881, Q9JMH6 |
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| Catalog # | PA5-28886 |
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| Price | |
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| Order / More Info | TrxR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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