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| Antigenic Specificity | TrxR1 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 2.5 µg/mL, peptide-ELISA: 1:32000, Western Blot: 0.1-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TrxR1 Polyclonal Antibody. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence , that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in se |
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| Immunogen | n/a |
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| Other Names | TXNRD1; thioredoxin reductase 1; TR1; TXNR; GRIM-12; MGC9145; TR; TRXR1; KM-102-derived reductase-like factor; oxidoreductase; thioredoxin reductase GRIM-12 |
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| Gene, Accession # | Entrez: 7296; Uniprot: Q16881 |
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| Catalog # | PA5-18068 |
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| Price | |
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| Order / More Info | TrxR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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