| 产品详情 |
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| Antigenic Specificity | HRAS |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. These proteins function in signal transduction pathways. They can bind GTP and GDP, and they have intrinsic GTPase activity. HRAS undergoes a continuous cycle of de and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in the HRAS gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. This HRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-128 amino acids from the Central region of human HRAS. |
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| Immunogen | Human HRAS. |
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| Other Names | GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; N-terminally; HRAS; HRAS1; C-has/bas p21 protein; C-ras-Ki-2 activated oncogene; C-HA-RAS1; CTLO; H-ras; H-RASIDX; GTP- and GDP-binding peptide B; HAMSV; K-RAS; Ha-Ras1 proto-oncoprotein; N-ras; p21r...; N-terminally processed; v-Ha-ras Harvey Rat sarcoma viral oncogene homolog; C-BAS/HAS; RASH1; HRAS-Specific; P19 H-RasIDX Protein; Harvey Rat Sarcoma Viral Oncoprotein; Harvey Rat Sarcoma Viral Oncogene Homolog |
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| Gene, Accession # | Accession: NP_001123914.1, NP_005334.1, NP_789765.1, SwissProt: P01112 |
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| Catalog # | abx033667 |
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| Price | |
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| Order / More Info | HRAS Antibody from ABBEXA |
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| Product Specific References | n/a |
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