| 产品详情 |
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| Product Name | Aaptamine |
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| Description | A marine sponge alkaloid; an agonist of δ- and µ-opioid receptors (EC50s = 5.1 and 10.1 µM, respectively, in HEK293 cells expressing human recombinant receptors); a competitive antagonist of α-ARs (pA2s = 4.88 and 5.43, respectively, in isolated rabbit aorta and renal artery); inhibits growth of HeLa cervical cancer (IC50 = 15 µg/ml) and K562 leukemia (GI50 = 10 µM) cells; induces cell cycle arrest in the G2/M phase in K562 leukemia and MG63 osteosarcoma cells; inhibits chymotrypsin-, caspase-, and trypsin-like activity in a partially purified rat liver proteasome preparation (IC50s = 1.6, 2.7, and 18 µg/ml, respectively); dose-dependently activates p21 independent of p53 in MG63 cells from 20-50 µM; decreases immobility time in the forced swim test in mice at 40 mg/kg |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 85547-22-4 |
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| Catalog # | 24297-1 |
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| Price | |
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| Order / More Info | Aaptamine from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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