| 产品详情 |
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| Product Name | BAY 57-1293 |
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| Description | An orally bioavailable helicase-primase inhibitor; inhibits the ATPase activity of HSV helicase-primase (IC50 = 30 nM); inhibits HSV replication in Vero cells (IC50 = 20 nM for both HSV-1 and HSV-2); active against porcine and bovine HSV strains (IC50s = 5 and 0.12 µM, respectively); effective against HSV-1 and HSV-2 in a lethal challenge model (ED50 = 0.5 mg/kg in mice and rats) and in a zosteriform spread model, at a dose of 15 mg/kg, in mice and Lewis rats; reduces levels of Aβ and phosphorylated Tau production in HSV-1 infected Vero cells |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BAY57-1293 BAY571293 pritelivir 571293 HSV1 HSV2 |
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| Gene, Accession, CAS # | CAS: 348086-71-5 |
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| Catalog # | 22129-5 |
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| Price | |
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| Order / More Info | BAY 57-1293 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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