| 产品详情 |
| Edit |   |
|---|
| Product Name | Oridonin |
|---|
| Description | A diterpenoid with anti-inflammatory and anticancer properties; an inhibitor of AKT1 and AKT2 (IC50s = 8.4 and 8.9 µM, respectively); inhibits proliferation of KYSE70, KYSE410, and KYSE450 esophageal cancer cells, halts the cell cycle at the G2/M phase, and induces apoptosis at 20 µM; decreases the protein levels of phosphorylated AKT and reduces AKT activity; reduces tumor growth in patient-derived mouse tumor models at 40 and 160 mg/kg; an inhibitor of NLRP3 inflammasome assembly and activation; inhibits inflammation in wild-type, but not Nlrp3-/-, mice in a model of high-fat diet-induced type 2 diabetes at 3 mg/kg |
|---|
| Size | 100 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | NSC 250682 |
|---|
| Gene, Accession, CAS # | CAS: 28957-04-2 |
|---|
| Catalog # | 25665-100 |
|---|
| Price | |
|---|
| Order / More Info | Oridonin from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|