产品详情 |
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Product Name | Vesnarinone |
Description | A PDE3 inhibitor and ERG1 channel blocker (IC50s = 10.7, 13.2, and 1.1 µM for PDE3A, PDE3B, and ERG1, respectively); increases contractile tension in isolated ventricular muscles of dog, cat, rabbit, and guinea pig in a dose-dependent manner; increases right ventricular pressure with no effect on heart rate in dog models of tricuspid insufficiency- and pulmonary stenosis-induced congestive heart failure; increases contractility and coronary flow while decreasing heart rate in a guinea pig model of aortic stenosis-induced congestive heart failure |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | OPC 8212 |
Gene, Accession, CAS # | CAS: 81840-15-5 |
Catalog # | 23489-10 |
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Order / More Info | Vesnarinone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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