产品名称 ON-123300 from CAYMAN CHEMICAL COMPANY
产品货号 19902-10
产品价格 现货询价,电话:010-67529703
产品规格 10 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameON-123300
DescriptionA multi-kinase inhibitor; inhibits ARK5, Cdk4, and Cdk6 (IC50s = 3.87, 9.82, and 4.95 nM, respectively); inhibits FYN, PDGFRβ, Abl, and PI3Kδ (IC50s = 11.09, 26, 53.32, and 144 nM, respectively) among others; inhibits proliferation in a panel of 38 cancer cell lines (GI50s = 0.05-5 µM); also inhibits proliferation of U87 glioma cells (IC50 = 3.4 µM); reduces tumor growth in an MDA-MB-231 mouse xenograft model at 50 mg/kg every other day
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesON123300 CDK4 Ark-5 PDGFR-β FGFR1 PI3K-δ u-87 G2-M MDAMB MB231 MDAMB231cdk-4-6
Gene, Accession, CAS #CAS: 1357470-29-1
Catalog #19902-10
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Order / More InfoON-123300 from CAYMAN CHEMICAL COMPANY
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