产品详情 |
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Product Name | AZD1480 |
Description | A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM); displays good pharmacokinetics in vivo, inhibits STAT3 and STAT5 activation in vivo, and suppresses tumorigenesis in mouse xenografts harboring constitutive STAT3 activity |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | JAK2 JAK 2 STAT3 STAT 3 STAT5 STAT 5 AZD 1480 janus-associated kinase |
Gene, Accession, CAS # | CAS: 935666-88-9 |
Catalog # | 10702-5 |
Price | |
Order / More Info | AZD1480 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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