| 产品详情 |
| Edit |   |
|---|
| Product Name | AZD 9496 |
|---|
| Description | A SERD (IC50 = 0.138 nM for ERα downregulation); selective for ERα compared to other nuclear hormone receptors (IC50s = 0.0008, 0.54, 0.92, and 30 µM for ERα, PR, GR, and AR, respectively); decreases ERα activity (IC50 = 0.282 nM for PR antagonism); reduces proliferation of MCF-7 breast cancer cells (IC50 = 0.0398 nM); inhibits MCF-7 xenograft growth in mice in a dose-dependent manner, |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | AZD9496 ER-α ERa MCF7 |
|---|
| Gene, Accession, CAS # | CAS: 1639042-08-2 |
|---|
| Catalog # | 21805-1 |
|---|
| Price | |
|---|
| Order / More Info | AZD 9496 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|