| 产品详情 |
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| Product Name | AZD 9291 |
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| Description | An irreversible inhibitor of EGFR sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type EGFR (IC50 = 480 nM); inhibits tumor growth in a xenograft mouse model at oral doses of 5-10 mg/kg |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1421373-66-1 inhibitor epidermal growth factor receptor EGFR mutants tumor cancer biochemical inhibit kinase AZD9291 T790M mutation wild-type IGF1R hERG tumor growth xenograft mouse model mice oral non-small-cell lung |
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| Gene, Accession, CAS # | CAS: 1421373-65-0 |
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| Catalog # | 16237-5 |
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| Price | |
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| Order / More Info | AZD 9291 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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