| 产品详情 |
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| Product Name | AZD 8931 |
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| Description | A reversible inhibitor of ErbB1/EGFR, ErbB2/HER2, and ErbB3/HER3 (IC50s = 4, 3, and 4 nM, respectively, for autophosphorylation); suppresses cell growth and induces apoptosis in SUM149 and FC-IBC-02 human breast cancer cell lines at 0.01, 0.1, and 1 µM; inhibits tumor growth in BT474c, Calu-3, LoVo, FaDu, and PC-9 mouse xenograft models from 6.25-50 mg/kg; inhibits inflammatory breast cancer tumor growth in a mouse xenograft model when administered in combination with paclitaxel at 25 mg/kg per day |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Sapitinib |
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| Gene, Accession, CAS # | CAS: 848942-61-0 |
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| Catalog # | 24196-1 |
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| Price | |
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| Order / More Info | AZD 8931 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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