| 产品详情 |
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| Antigenic Specificity | CD53 |
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| Clone | OX-79 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgM, κ |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse CD53. CD53 is a pan-leukocyte surface glycoprotein which spans the plasma membrane four times and is a member of the transmembrane 4 superfamily (TM4SF). CD53 is highly conserved in evolution, mouse CD53 was 91% identical to rat and 82% identical to human CD53. Mouse CD53 has a molecular mass of 35-45 kD and expresses on virtually all peripheral leukocytes, immature CD4-CD8- double negative thymocytes, and functionally mature CD4+CD8- or CD4-CD8+ single positive subsets. CD53 is proposed to play an important role in thymopoiesis and leukocyte signal transduction. It was reported that CD53 interact with a number of proteins, including CD2, CD9, CD19, and CD21. Cross-linking of CD53 promotes B cell activation. It was found that there is a strong correlation between CD53 expression and positive selection of thymocytes. |
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| Immunogen | BAB/14 mouse macrophage cell line RAW264 |
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| Other Names | MOX44, OX-44, Tspan-25 |
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| Gene, Accession # | Gene ID: 12508 |
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| Catalog # | 124701 |
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| Price | |
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| Order / More Info | CD53 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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