产品详情 |
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Antigenic Specificity | CD90.2 |
Clone | 30-H12 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, κ |
Format | Pacific Blue™ conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pacific Blue™ anti-mouse CD90.2. CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30-H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes. |
Immunogen | Mouse thymus or spleen |
Other Names | Thy-1.2 |
Gene, Accession # | Gene ID: 21838 |
Catalog # | 105324 |
Price | |
Order / More Info | CD90.2 Antibody from BIOLEGEND |
Product Specific References | PubMed: 17641035,23589894 |
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