| 产品详情 |
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| Antigenic Specificity | CD45R |
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| Clone | RA3-6B2 |
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| Host Species | Rat |
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| Reactive Species | mouse, human, cross-reactivity: cat |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), CyTOF®, IHC-F, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse/human CD45R/B220. CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
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| Immunogen | Abelson murine leukemia virus-induced pre-B tumor cells |
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| Other Names | B220 |
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| Gene, Accession # | Gene ID: 19264, 5788 |
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| Catalog # | 103202 |
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| Price | |
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| Order / More Info | CD45R Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 18077787,20512127,21276089,24039898 |
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| 产品资料 |
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