产品详情 |
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Antigenic Specificity | CD45RB |
Clone | C363-16A |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | Pacific Blue™ conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pacific Blue™ anti-mouse CD45RB. CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naïve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1. |
Immunogen | Cloned mouse Th2 cell lines |
Other Names | n/a |
Gene, Accession # | Gene ID: 19264 |
Catalog # | 103315 |
Price | |
Order / More Info | CD45RB Antibody from BIOLEGEND |
Product Specific References | n/a |
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