产品名称 LOXO-195 from CAYMAN CHEMICAL COMPANY
产品货号 27062-10
产品价格 现货询价,电话:010-67529703
产品规格 10 mg
产品品牌 CAYMAN CHEMICAL COMPANY
产品概述
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Product NameLOXO-195
DescriptionAn inhibitor of TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 = 1.9 nM); selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = ≤5 nM) over Trk fusion-negative cell lines; reduces tumor growth in TrkA-dependent KM12, as well as NIH 3T3 ΔTrkA, ΔTrkA + TrkAG595R, and ΔTrkA + TrkAG667C mouse xenograft models at ≥30 mg/kg
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesSelitrectinib
Gene, Accession, CAS #CAS: 2097002-61-2
Catalog #27062-10
Price
Order / More InfoLOXO-195 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
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