产品详情 |
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Antigenic Specificity | C5L2 |
Clone | 1D9-M12 |
Host Species | Mouse |
Reactive Species | human, African green, baboon, cynomolgus, rhesus |
Isotype | IgG2a, κ |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human C5L2. C5L2 (C5a receptor-like 2) is a seven-transmembrane orphan receptor, also known as GPR77, which shares significant homology to C5a receptor (CD88). But it is a decoy receptor without G-protein coupling. C5L2 is co-expressed with C5aR on many kinds of cells, such as neutrophils, immature dendritic cells, mast cells, macrophages, and astrocytes. C5L2 binds C5a with similar high affinity as C5aR and relatively higher affinity for C5a-des-Arg than with C5aR. Clone 1D9-M12 is known to block C5a binding to C5L2, but does not react with C5a receptor. |
Immunogen | n/a |
Other Names | GPR77, C5a receptor-like 2, C5a anaphylatoxin chemotactic receptor |
Gene, Accession # | Gene ID: 27202 |
Catalog # | 342404 |
Price | |
Order / More Info | C5L2 Antibody from BIOLEGEND |
Product Specific References | n/a |
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