| 产品详情 |
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| Antigenic Specificity | MRP1 (ABCC1) |
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| Clone | QCRL-2 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b, κ |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Intracellular Staining for Flow Cytometry (ICFC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor® 647 anti-human/mouse MRP1 (ABCC1). MRP1 is a 190 kD integral membrane phosphoglycoprotein. It is a member of the human ATP-binding cassette transporter multidrug resistance protein1 (MRP1), encoded by ABCC1. MRP1 is expressed in most normal tissues, with higher levels in the testes, lung, skin, small intestine, colon, kidney, placenta, peripheral blood mononuclear cells, and skeletal muscle. ABCC1 encodes plasma membrane proteins that have important physiological transport functions and mediate a variety of xenobiotics against their concentration gradients. MRP1 plays an important role in the extrusion of drugs from the cell and their over expression can be a cause of failure of anticancer and antimicrobial chemotherapy. |
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| Immunogen | QCRL-2 was raised against membranes prepared from the human small cell lung cancer cell line, H69AR, which highly over expresses MRP1. |
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| Other Names | ABC29, ABCC, GS-X, MRP, Multidrug resistance-associated protein 1, LTC4 transporter, leukotriene C(4) transporter |
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| Gene, Accession # | Gene ID: 4363 |
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| Catalog # | 370204 |
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| Price | |
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| Order / More Info | MRP1 (ABCC1) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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