| 产品详情 |
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| Antigenic Specificity | CD88 |
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| Clone | 20/70 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b, κ |
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| Format | purified, azide-free |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Block |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF™ Purified anti-mouse CD88 (C5aR). CD88 is a single chain protein with seven membrane-spanning regions and a molecular weight of 43 kD. CD88 is expressed by neutrophils, eosinophils, and monocytes. There have been reports of CD88 expression in non-immune cells such as glial cells, cerebellar granule cells, cardiomyocytes, and vascular endothelial cells. CD88 is coupled to heterotrimeric G proteins such as Gi, and after C5a binding, the signal transduced by CD88 results in the activation of PLCβ, PI-3 kinase, and PLA2, among other molecules, resulting in chemotaxis, granule enzyme release, and superoxide anion production. |
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| Immunogen | mC5aR transfected cells |
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| Other Names | C5a ligand, C5a anaphylatoxin receptor, C5AR, C5R1, C5AR1 |
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| Gene, Accession # | Gene ID: 12273 |
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| Catalog # | 135804 |
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| Price | |
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| Order / More Info | CD88 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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