| 产品详情 |
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| Antigenic Specificity | CD49b (pan-NK cells) |
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| Clone | DX5 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgM, κ |
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| Format | APC-Cyanine7 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC/Cyanine7 anti-mouse CD49b (pan-NK cells). DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen. |
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| Immunogen | IL-2-propagated NK1.1+ cells from C57BL/6 mice |
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| Other Names | α2 integrin, VLA-2 α chain, DX5, Integrin α2 chain |
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| Gene, Accession # | Gene ID: 16398 |
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| Catalog # | 108919 |
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| Price | |
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| Order / More Info | CD49b (pan-NK cells) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 16849474,20048123,20512127,21270406,21557788,21864623,22609473,22984178,25150294 |
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