| 产品详情 |
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| Antigenic Specificity | CD49d |
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| Clone | MRα4-1 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG2a, κ |
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| Format | fluorescein (FITC) conjugate |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FITC anti-rat CD49d. CD49d is a 150 kD glycoprotein, also known as integrin α4 or VLA-4 α chain. It is expressed as a heterodimer with either of two β chains, β1 or β7. The α4β1 integrin (also known as VLA-4, CD49d/CD29) is expressed on peripheral T and B lymphocytes, thymocytes, and monocytes, while the α4β7 integrin (also known as LPAM-1) is expressed on peripheral lymphocytes. The α4β1 and α4β7 integrins mediate cell-cell and cell-matrix interactions by interacting with the ligands CD106 (VCAM-1), MAdCAM-1, and fibronectin. Soluble MRα4-1 antibody can partially inhibit in vitro binding of VCAM-1 and mast cells to fibronectin and inhibit mast cell degranulation. Immobilized MRα4-1 antibody can enhance mast cell degranulation in vitro. |
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| Immunogen | RBL-2H3 rat basophilic leukemia cell line |
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| Other Names | Integrin α4 chain, α4 integrin, VLA-4 α chain, integrin a4 |
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| Gene, Accession # | Gene ID: 311144 |
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| Catalog # | 200103 |
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| Price | |
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| Order / More Info | CD49d Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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