| 产品详情 |
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| Antigenic Specificity | CD49c |
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| Clone | ASC-1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IP, Western Blot (WB), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD49c (integrin α3). CD49c is a 150 kD α integrin chain known as α3 integrin or VLA-3 α chain. It is a type I transmembrane glycoprotein which is proteolytically cleaved into two disulfide linked fragments of 125 kD and 30 kD. CD49c forms a heterodimer with integrin β1 (α3β1, CD49c/CD29, VLA-3) and is expressed by many types of adhesion cells, such as endothelial cells, epithelial cells, and dermal fibroblasts. Weak expression has been reported on leukocytes. VLA-3 plays a role in cell-cell and cell-matrix adhesion through binding Kalinin, collagen, laminin-1, laminin-5, entactin, and fibronectin. |
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| Immunogen | Human squamous cell carcinoma cell line SCC-9 |
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| Other Names | α3 integrin, integrin α3 chain, VLA-3 α chain, VLA3a, ITGA3 |
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| Gene, Accession # | Gene ID: 3675 |
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| Catalog # | 343802 |
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| Price | |
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| Order / More Info | CD49c Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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