| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD49c |
|---|
| Clone | ASC-1 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, κ |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 25 tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PE anti-human CD49c (integrin α3). CD49c is a 150 kD α integrin chain known as α3 integrin or VLA-3 α chain. It is a type I transmembrane glycoprotein which is proteolytically cleaved into two disulfide linked fragments of 125 kD and 30 kD. CD49c forms a heterodimer with integrin β1 (α3β1, CD49c/CD29, VLA-3) and is expressed by many types of adhesion cells, such as endothelial cells, epithelial cells, and dermal fibroblasts. Weak expression has been reported on leukocytes. VLA-3 plays a role in cell-cell and cell-matrix adhesion through binding Kalinin, collagen, laminin-1, laminin-5, entactin, and fibronectin. |
|---|
| Immunogen | Human squamous cell carcinoma cell line SCC-9 |
|---|
| Other Names | α3 integrin, integrin α3 chain, VLA-3 α chain, VLA3a, ITGA3 |
|---|
| Gene, Accession # | Gene ID: 3675 |
|---|
| Catalog # | 343803 |
|---|
| Price | |
|---|
| Order / More Info | CD49c Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|