| 产品详情 |
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| Antigenic Specificity | CD49b |
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| Clone | HMα2 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | biotin conjugate |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Biotin anti-mouse CD49b. CD49b is a 150 kD glycoprotein, also known as α2 integrin, VLA-2 α chain, Integrin α2 chain, and HMα2. It is a member of the integrin family, expressed on NK cells, a subset of splenic CD4+ T cells, NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, epithelial cells, and platelets. By associating with CD29 (integrin β1 subunit), CD49b forms the VLA-2 (integrin α2β1 ) complex. It plays a critical role in both adhesion and lymphocyte activation. The primary ligands for CD49b are collagen, laminin, and fibronectin. The HMα2 antibody has been shown to be useful for partially blocking CD49b mediated interactions with collagen. Additionally, this antibody blocks staining of splenic NK cells by the monoclonal antibody DX5. |
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| Immunogen | Mouse colon carcinoma cell line Colon26 |
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| Other Names | α2 integrin, VLA-2 α chain, Integrin α2, HMa2 |
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| Gene, Accession # | Gene ID: 16398 |
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| Catalog # | 103521 |
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| Price | |
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| Order / More Info | CD49b Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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