| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD86 |
|---|
| Clone | IT2.2 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, African green, baboon, capuchin monkey, common marmoset, cotton-topped tamarin, chimpanzee, cynomolgus, rhesus |
|---|
| Isotype | IgG2b, κ |
|---|
| Format | Brilliant Violet 785™ conjugate |
|---|
| Size | 100 tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Brilliant Violet 785™ anti-human CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
|---|
| Immunogen | n/a |
|---|
| Other Names | B7-2, B70 |
|---|
| Gene, Accession # | Gene ID: 942 |
|---|
| Catalog # | 305442 |
|---|
| Price | |
|---|
| Order / More Info | CD86 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|