| 产品详情 |
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| Product Name | (-)-Securinine |
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| Description | An alkaloid; reduces proliferation of SW480 colon adenocarcinoma cells in a dose- and time-dependent manner; decreases viability of HL-60 leukemia cells (IC50s = 47.88, 23.85, and 18.87 µM at 24, 48, and 72 hours post-treatment, respectively); induces cell cycle arrest at the G1/S phase and decreases PI3K, Akt, and mTOR gene expression in a dose-dependent manner; inhibits GABA and GABA-activated benzodiazepine binding to rat brain membranes (IC50s = 57 and 101 µM, respectively); induces clonic and tonic convulsions in mice at 5.2 mg/kg, |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | L-Securinine|NSC 107413 |
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| Gene, Accession, CAS # | CAS: 5610-40-2 |
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| Catalog # | 24902-50 |
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| Price | |
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| Order / More Info | (-)-Securinine from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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