产品名称 Tofogliflozin (hydrate) from CAYMAN CHEMICAL COMPANY
产品货号 23509-25
产品价格 现货询价,电话:010-67529703
产品规格 25 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameTofogliflozin (hydrate)
DescriptionA potent inhibitor of SGLT2 (Kis = 2.9, 14.9, and 6.4 nM for human, rat, and mouse SGLT2, respectively); selective for SGLT2 (IC50 = 2.9 nM) over other SGLTs (IC50s = >1,500 nM for SGLT1 and 3-6); reduces plasma glucose concentration and increases renal glucose clearance in Zucker diabetic fatty rats in a dose-dependent manner when administered at doses ranging from 3-10 mg/kg; reduces hyperglycemia in non-fasted db/db mice and decreases postprandial hyperglycemia in GK rats, a non-obese model of type 2 diabetes with glucose intolerance,
Size25 mg
Concentrationn/a
Applicationsn/a
Other Names903565-83-3 Deberza CSG-452 SGLT-1 2 CSG452 SGLT3 SGLT4 SGLT5 SGLT6
Gene, Accession, CAS #CAS: 1201913-82-7
Catalog #23509-25
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Order / More InfoTofogliflozin (hydrate) from CAYMAN CHEMICAL COMPANY
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