| 产品详情 |
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| Product Name | Tofogliflozin (hydrate) |
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| Description | A potent inhibitor of SGLT2 (Kis = 2.9, 14.9, and 6.4 nM for human, rat, and mouse SGLT2, respectively); selective for SGLT2 (IC50 = 2.9 nM) over other SGLTs (IC50s = >1,500 nM for SGLT1 and 3-6); reduces plasma glucose concentration and increases renal glucose clearance in Zucker diabetic fatty rats in a dose-dependent manner when administered at doses ranging from 3-10 mg/kg; reduces hyperglycemia in non-fasted db/db mice and decreases postprandial hyperglycemia in GK rats, a non-obese model of type 2 diabetes with glucose intolerance, |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 903565-83-3 Deberza CSG-452 SGLT-1 2 CSG452 SGLT3 SGLT4 SGLT5 SGLT6 |
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| Gene, Accession, CAS # | CAS: 1201913-82-7 |
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| Catalog # | 23509-10 |
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| Order / More Info | Tofogliflozin (hydrate) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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