产品名称 BIBF 1120 from CAYMAN CHEMICAL COMPANY
产品货号 11022-5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameBIBF 1120
DescriptionA VEGFR, FGFR, and PDGFR inhibitor (IC50s = 13-34, 37-610, and 59 and 65 nM for VEGFR1-3, FGFR1-4, and PDGFRα and β, respectively); selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases, however, it also inhibits Flt-3, Lck, Lyn, and Src (IC50s = 16-156 nM); inhibits growth factor-dependent proliferation of HUVECs, HSMECs, HUASMCs, and BRP cells (EC50s = 7-290 nM); reduces tumor microvessel density and the number of PDGFRβ-expressing perivascular cells in a FaDu head and neck small cell carcinoma mouse xenograft model at 100 mg/kg; inhibits tumor growth in a Caki-1 renal cancer mouse xenograft model
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesNintedanib
Gene, Accession, CAS #CAS: 656247-17-5
Catalog #11022-5
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Order / More InfoBIBF 1120 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
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