产品详情 |
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Antigenic Specificity | IL-34 |
Clone | C051-77 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2c, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-IL-34. IL-34 is a glycoprotein that plays important roles in the proliferation, survival, and differentiation of monocytes and macrophages. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage development. IL-34 also promotes inflammatory processes and regulates osteoclast proliferation, differentiation, and bone reabsorption. |
Immunogen | Recombinant mouse IL-34 produced in CHO cells. |
Other Names | IL34, Interleukin 34, Chromosome 16 Open Reading Frame 77, C16orf77 |
Gene, Accession # | Gene ID: 762577 |
Catalog # | 675102 |
Price | |
Order / More Info | IL-34 Antibody from BIOLEGEND |
Product Specific References | n/a |
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