产品详情 |
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Antigenic Specificity | CD134 (OX-40) |
Clone | OX-86 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | PerCP-Cyanine5.5 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PerCP/Cyanine5.5 anti-mouse CD134 (OX-40). CD134 is a type I integral membrane protein also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a costimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases. |
Immunogen | Recombinant mouse OX-40-CD4 chimeric protein |
Other Names | TNFRSF4, ACT35, OX-40 |
Gene, Accession # | Gene ID: 22163 |
Catalog # | 119425 |
Price | |
Order / More Info | CD134 (OX-40) Antibody from BIOLEGEND |
Product Specific References | n/a |
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