| 产品详情 |
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| Antigenic Specificity | CD134 (OX-40) |
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| Clone | OX-86 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | Brilliant Violet 421™ conjugate |
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| Size | 125 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Brilliant Violet 421™ anti-mouse CD134 (OX-40). CD134 is a type I integral membrane protein also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a costimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases. |
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| Immunogen | Recombinant mouse OX-40-CD4 chimeric protein |
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| Other Names | TNFRSF4, ACT35, OX-40 |
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| Gene, Accession # | Gene ID: 22163 |
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| Catalog # | 119411 |
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| Price | |
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| Order / More Info | CD134 (OX-40) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 21276089 |
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